This open access 2018 review by Paolo Governa and co-workers from the University of Siena and the Italian Society of Phytotherapy provides an overview of the use of medicinal plants in the management of diabetes, with particular regard to evidence of clinical effectiveness of medicinal plants in controlling diabetes-related symptoms.
The authors emphasise the following species enlisted in WHO monographs with indication of use for diabetes:
- Holy basil, Ocimum tenuiflorum L., leaves.
- Fenugreek, Trigonella foenum-graecum L., seeds.
- Onion, Allium cepa L., bulb.
- Neem, Azadirachta indica A. Juss., leaves.
- Bitter melon, Momordica charantia L., fruit.
- Korean ginseng, Panax ginseng C.A. Meyer, roots.
- American ginseng, Panax quinquefolius L., roots.
- Rehmannia glutinosa (Gaertn.) DC., roots.
Many of these are used of diabetes in traditional medical systems or described in pharmacopoeias for this use. The authors consider that for the first two, holy basil and fenugreek, their use in diabetes is supported by clinical data.
The authors also discuss some other species which are attracting the interest of the scientific community for their promise in treating diabetes.
The authors comment that there is a crucial need for stronger evidence-based data.
Citation Governa P, Baini G, Borgonetti V, Cettolin G, Giachetti D, Magnano AR, Miraldi E, Biagi M. Phytotherapy in the Management of Diabetes: A Review. Molecules. 2018; 23(1):105. https://doi.org/10.3390/molecules23010105