This interesting paper presents an overview of the existing literature published since the year 2000, seeks to identify some repeatedly found seasonal trends and discusses some possible explanations for these trends.
3. Physiological Effects of Phytochemicals from C. sativum
Flavonoids: A flavonoid-rich fraction was found to have hypotensive activity.
Quercetin (a flavonoid): A quercetin-rich aqueous ethanolic extract inhibits α-amylase, α-glucosidase and lipase, and thus potentially has antidiabetic and anti-obesity effects.
Polyphenols: A polyphenol-rich extract inhibits angiotensin-converting enzyme thus potentially has a antihypertensive effect.
Isocoumarins: Isocoumarin aglycones and (to a lesser degree) isocoumarin glycosides (cilantroside A and B) have been found to have neurotrophic / neuroprotective effects by stimulation of nerve growth factor. The aglycones of isocoumarins also showed anti-inflammatory effects.
Phenolic glycosides: The phenolic glycosides daphnin and benzyl-O-β-d-glucoside have also been found to stimulate nerve growth factor.
Sterols: Plant sterols have hypocholesterolaemic effects.
Essential oil: Prominent activities against diabetes, microbial infections, and inhibitory to acetylcholinterase.
Other: A linalool, ascorbyl palmitate and petroselinic acid-rich petroleum ether extract of coriander seeds reduces oxidative stress, is hypolipidaemic, hypoglycaemic, and preventative against diabetic nephropathy.
4. Cardiovascular Benefits of C. sativum
A systematic review was carried out of studies investigating the potential cardiovascular benefits of C. sativum.
Studies have demonstrated the cardioprotective benefits of C. sativum. These include its effect as an antioxidant, antihypertensive, anti-atherogenic, antiarrhythmic, as well as the improvement of other factors that may lead to cardiovascular disease (CVD), such as altered lipid profile, hyperglycaemia and cardiac biomarkers or enzymes.
Most of the studies included in the review were in vivo studies carried out on laboratory animals. Only two were human studies. These latter demonstrated hypolipidaemic, hypocholesterolaemic, hypotensive and antioxidant effects of coriander seed powder. As to plant parts, the majority of the studies included investigated the effects of the seeds. The two studies on the leaves showed hypolipidaemic, hypotensive, normoglycaemic and antioxidant effects.
The authors comment that more in vitro studies are needed to elucidate mechanisms of action.
This study is an ethnobotanical review of herbs traditionally used to treat Cystitis in the Rif, Northern Morocco.
Of the 60 plant species described, Capparis spinosa L. (caper) was the most commonly used – as a decoction of the leaves – followed by Apium graveolens L. (celery) – whole plant as an infusion – and Ziziphus vulgaris Lam. (jujube) – fruit, eaten.
The authors of this study surveyed the use by herbal healers of plant species found in Kerman Province, south-east Iran. They note that traditional (folk) medicine is a major component of healthcare in south-east Iran.
The study findings suggest that plants in the Asteraceae and Apiaceae families are used for the treatment of gastrointestinal disorders, Lamiaceae plants for respiratory and gastrointestinal ailments, and Apocynaceae and Euphorbiaceae plants for dermatological problems.
A full table of the medicinal plants identified and their uses by local herbal healers can be found here.
Hosseini, S.H., Bibak, H., Ghara, A.R. et al. Ethnobotany of the medicinal plants used by the ethnic communities of Kerman province, Southeast Iran. J Ethnobiology Ethnomedicine17, 31 (2021). https://doi.org/10.1186/s13002-021-00438-z .
In a previous post I presented a graphic about the Common Nettle (Urtica dioica) in Western Herbalism. This post complements that one, and deals with the use of the herb in Traditional Chinese Medicine (TCM) and Ayurveda.
If the image is too small for you to read the words, enlarge your window by holding down ‘Control’ and scrolling up with your mouse wheel.