Anti-Cancer Activity of Limonene

Lemons by Dwayne Madden via Flickr, reproduced according to Creative Commons licence CC BY 2.0.

Limonene is an abundant monoterpene in essential oils of citrus fruit peels (Rutaceae).

This systemic review highlights limonene as “an abundant natural molecule with low toxicity and pleiotropic pharmacological activity in cancer cells, targeting various cell‐signaling pathways critically involved in the initiation, growth, and chemoresistance of cancer cells“. (My italics.)

Gomes de Araújo-Filho H. et al. (2021). Anticancer activity of limonene: A systematic review of target signaling pathways. Phytotherapy Research. 17th April 2021. https://doi.org/10.1002/ptr.7125 .

Copyright © Robert Hale 2021.

Significance and Use of Walnut: A Review

Persian Walnut. Photo from Piklist.com. Free to use.

This review summarises ethnobotanical use, pharmacology, nutritional value, preclinical and clinical studies, toxicity, other uses and current research prospects of Juglans regia L. (Walnut).

Walnut leaf has been found to possess the following properties of potential clinical significance:

  • Antimicrobial, antifungal and anti-viral.
  • Anti-inflammatory.
  • Antidiabetic.
  • Antityrosinase (against skin hyperpigmentation).
  • Anti-cancer

Walnut bark shares some of these properties but in particular, it is anthelmintic.

Walnut fruit (the nut) is antidepressant, antitrigliceridaemic, hepatoprotective, anti-amyloidogenic improves motor and cognitive performance.

Nael Abu Taha and Mohammed A. Al-wadaan (2021) Significance and use of walnut, Juglans regia Linn: A review. Advanced Journal of Microbiology Research ISSN 2736-1756Vol. 15 (1), pp. 001-010, January, 2021.

Phytochemistry of Medicinal Plants Used in Romania

This literature review details the phytochemistry of some commonly used medicinal plants in Romania. Many of the plants listed are common to use in other European countries. A PDF download of the full article is available from the link below.

Isabelle P, Monica B (2021) Highlighting the Compounds with Pharmacological Activity from Some Medicinal Plants from the Area of Romania. Med Aromat Plants (Los Angeles) 10: 370.

https://www.researchgate.net/profile/Monica-Butnariu/publication/349494201_Medicinal_Aromatic_Plants_Highlighting_the_Compounds_with_Pharmacological_Activity_from_Some_Medicinal_Plants_from_the_Area_of_Romania/