Limonene is an abundant monoterpene in essential oils of citrus fruit peels (Rutaceae).
This systemic review highlights limonene as “an abundant natural molecule with low toxicity and pleiotropic pharmacological activity in cancer cells, targeting various cell‐signaling pathways critically involved in the initiation, growth, and chemoresistance of cancer cells“. (My italics.)
Gomes de Araújo-Filho H. et al. (2021). Anticancer activity of limonene: A systematic review of target signaling pathways. Phytotherapy Research. 17th April 2021. https://doi.org/10.1002/ptr.7125 .
This review summarises ethnobotanical use, pharmacology, nutritional value, preclinical and clinical studies, toxicity, other uses and current research prospects of Juglans regia L. (Walnut).
Walnut leaf has been found to possess the following properties of potential clinical significance:
Antimicrobial, antifungal and anti-viral.
Antityrosinase (against skin hyperpigmentation).
Walnut bark shares some of these properties but in particular, it is anthelmintic.
Walnut fruit (the nut) is antidepressant, antitrigliceridaemic, hepatoprotective, anti-amyloidogenic improves motor and cognitive performance.
Nael Abu Taha and Mohammed A. Al-wadaan (2021) Significance and use of walnut, Juglans regia Linn: A review. Advanced Journal of Microbiology Research ISSN 2736-1756Vol. 15 (1), pp. 001-010, January, 2021.