Phytotherapy for Polycystic Ovary Syndrome

Flax (Linum usitatissimum L.). Public domain photo from Pikist.com.

Azin and Khazali (2021) of Shahid Beheshti University, Tehran, Iran, carried out a literature review of studies concerning the potential role of herbs in the treatment of polycystic ovary syndrome (PCOS), a frequently encountered female complaint.

The 31 studies reviewed collectively covered 25 different herbs, two Traditional Chinese Medicine (TCM) and one Ayurvedic formulae, and four isolates from herbs (berberine, curcumin, soy isoflavone and quercetin).

Of the 25 herbs in the studies, 9 are native to the area of interest of this blog, the Mediterranean and Near East: aloe vera (Aloe
barbadensis
), anise (Pimpinella anisum), fennel (Foeniculum
vulgare
), fenugreek (Trigonella foenum-graecum), flax seed (Linum usitatissimum), hazelnut (Corylus avellana), liquorice (Glycyrrhiza glabra), nettle and pomegranate (Punica granatum).

Of the studies done with these herbs, three were done with human subjects, the other with animal models. Two were done with women with PCOS. Some of the studies showed clinical benefits for PCOS, others showed improved hormone profiles consistent with better potential PCOS outcomes, others still improved secondary complications of PCOS such as metabolic syndrome.

The table below summarises in very basic form some data from the review.

HerbClinical benefits for PCOSImproved hormone profileImproved complications of PCOSHuman/
Animal
Aloe vera**A
Anise**A
Fennel*A
Fenugreek**H
Flax seed**H
Hazlenut**A
Liquorice**A, H
Nettle*A
Pomegranate**A
Citation:

Azin F. & Khazali H. (2021). Phytotherapy of polycystic ovary syndrome: A review. International Journal of Reproductive BioMedicine Volume 20, Issue no. 1, https://doi.org/10.18502/ijrm.v20i1.10404